Spravato (esketamine) Nasal Spray for Treatment-Resistant Depression Available in Los Angeles
Spravato (esketamine) nasal spray is the first FDA-approved nasal spray to be used in conjunction with oral antidepressants. Millions of men and women suffer with a form of depression, and many will experience treatment-resistant depression. Spravato was created to provide a more effective way to help those with this serious condition. Read on to learn more about esketamine and how Spravato works.
Benefits of Spravato
- Improve treatment-resistant depression
- Treat major depressive disorder
- FDA – approved
- Faster symptom reduction
Understanding Spravato esketamine for Depression
Spravato is a prescription medication used alongside antidepressants. It is a nasal spray containing esketamine that improves treatment-resistant depression and major depressive disorder. Spravato was approved by the FDA in 2019 to be used with oral antidepressants. Studies show that Spravato combined with antidepressants is 37% more effective than the pill alone.
Esketamine is made from the synthetic drug, Ketamine. Esketamine is more potent and works to heighten the levels of glutamate. Glutamate is a chemical messenger in the brain that, when in abundance, allows for better communication between brain cells. This effect very positively affects a person’s mood.
Adam Kaplin, M.D., Ph.D., a psychiatrist at Johns Hopkins Medicine, said this about esketamine: “For the first time in 60 years, we have a new antidepressant therapy that isn’t just a spinoff of existing drugs…“For some people, esketamine therapy is revolutionary, giving them the chance to experience life without depression for the first time in decades”.
How Spravato Works
Traditional antidepressants are slow to provide relief if any at all. It can take several weeks for any noticeable change. These common medications, typically prescribed for those with depression, work to increase naturally occurring chemicals like dopamine and serotonin. These naturally occurring chemicals are messengers that communicate with each other between brain cells. Spravato’s esketamine medication adds upon those efforts by increasing neurotransmitters so that the communication between brain cells is easier, better, and more efficient. Spravato used with antidepressants can provide faster relief than antidepressants taken alone.
The nasal spray is self-administered. A very low dose of esketamine is delivered in bursts through the nose. Spravato is administered under the supervision of a healthcare professional who will also monitor your symptoms for at least 2 hours after treatment.
Due to the nature of esketamine, Spravato nasal spray is only available through a restricted program and should be thoroughly researched and discussed with a doctor. Spravato has side effects and may not be right for everyone, as with all prescription medications. Protect your health and wellbeing by learning more about esketamine and Spravato.
Spravato Nasal Spray vs. Ketamine Infusion Therapy
Spravato and Ketamine infusion therapy can both provide relief in depression patients.
They act on the N-methyl-D-aspartate (NMDA) receptor in the brain. NMDA receptors play a role in learning, memory, and mood regulation. NMDA receptor dysfunction is linked to depression and other mental health disorders. Both Spravato and Ketamine infusions block the NMDA receptor.1 This increases the production of neurotransmitters like dopamine and glutamate, which improves cognition and mood.
A key difference between Spravato and Ketamine infusion therapy is how they’re administered. Ketamine goes into the body through an IV infusion for 45-60 minutes. Spravato is a nasal spray version of the drug. Patients can self-administer it, but we monitor them for two hours to ensure no side effects.
As far as dosage goes, Spravato is more potent. So, we generally give ketamine infusions at higher doses. The body metabolizes Ketamine differently when delivered intravenously. If you’re new to Spravato, we’ll start you on a lower dose and adjust according to how your body responds to it.
Spravato and Ketamine infusions share similar side effects:
- Blurred vision
- Increased blood pressure
Both treatments are safe when administered and monitored by a professional. Choose a reputable provider to get excellent results.
Spravato's Success Rate for Treating Depression
Many patients who have tried other forms of anti-depressants with no luck see success with Spravato. In a study, patients who took Spravato to treat their depression experienced a 55% remission rate at 32 weeks.2 It can be an effective treatment for addressing tough-to-treat depression.
Ideal candidates for Spravato are adults who have tried traditional antidepressants without success. It’s usually prescribed as part of an extensive treatment plan. This may include therapy and other medicine.
Though Spravato can be effective for some patients, it’s not suitable for everyone. Those with a history of the following shouldn’t use Spravato:
- Substance abuse or addiction
- Uncontrolled high blood pressure
- Vascular disorders
Determine your candidacy by scheduling a free consultation with Ketamine Therapy LA. We’ll go over your medical history and suggest a safe and effective treatment plan.
Spravato Nasal Spray FAQs
Spravato nasal spray is FDA-approved to treat treatment-resistant depression in adults. However, it’s not approved to treat anxiety disorders yet. Since anxiety and depression are related conditions, some may experience anxiety relief with Spravato. But there’s limited research showing its efficacy for this purpose.
Spravato cost in LA is different for each patient depending on various factors:
- Severity of depression
- Prescribed dosage
- Number of treatments
- Provider’s location and expertise
- Insurance coverage (where applicable)
Get an accurate quote for the treatment by consulting with a reputable provider like Ketamine Therapy LA. We can craft a custom treatment plan with a breakdown of costs.
Insurance coverage for Spravato varies depending on your healthcare provider and plan. It’s a specialty medication, so insurance policies may have unique eligibility requirements. Insurance companies may bill for the cost of the medication and administration separately. Call your insurance provider to find out coverage details and out-of-pocket costs.
Get the Spravato (esketamine) Nasal Spray in Los Angeles and West Hollywood
If you suffer from treatment-resistant depression or major depressive disorder, Spravato may be right for you. Ketamine Therapy LA is a premier provider of Ketamine and ketamine treatments in West Hollywood. We can help you learn more about this revolutionary medicine for depression and if it’s right for you. Schedule a consultation with us today to learn about Spravato by calling (323) 650-9883.
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Intranasal Esketamine (SpravatoTM) for Use in Treatment-Resistant Depression In Conjunction With an Oral Antidepressant. Published in National Library of Medicine. Link.
J&J’s Nasal Spray Spravato Beats Former AZ Drug Seroquel XR in Treatment-Resistant Depression Trial. Published in Fierce Pharma. Link.
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